Abstract: This experiment took E. coli as the research target flora. The antibacterial properties of Ti3C2/Co nanomaterials under near-infrared light (NIR) were studied by standard plate counting, live-dead bacteria staining, and observation of the bacterial surface structure under a scanning electron microscope. Hemolysis test, cck8 cytotoxicity test and migration test of umbilical vein endothelial cells were further verified its biological safety.The results showed that Ti3C2/Co nanomaterials were clear lamellar structures. The magnetic cobalt nanowires endowed Ti3C2/Co nanomaterials with controllable magnetic ability. Ti3C2/Co composite nanomaterials had good antibacterial properties, and its sterilization rate could reach 100% at a concentration of 250 μg/mL when combined with near-infrared light. At the same time, Ti3C2/Co composite nanomaterials showed excellent cell compatibility within a certain concentration range. This material had potential application prospects and could be used as an antibacterial agent in many fields such asmedical catheters, surgical instruments and antibacterial gauze.

Key words: Ti3C2/Co composite nanomaterials, near-infrared light(NIR), antibacterial activity, biological safety, antibacterial agent